Alpheus® Variant and Expression Detection Pipeline

Alpheus is an award-winning analysis software for large genome, transcriptome and methylome sequencing studies based on next-generation sequence data. Alpheus is designed to be used by scientists who are not experts in bioinformatics, statistics, software engineering or IT and who want to identify differences between sets of samples.

Personal Genomics at NCGR

Scientists are working with Illumina® to provide individual genome sequences.

NCGR uses its award-winning Alpheus® software system to provide a detailed analysis of your personal genome sequence. Based on NCGR's experience in sequencing genomes this involves comparing your individual genome sequence with the reference human genome sequence [alignment], identifying the points at which your genome differs (single nucleotide substitutions [SNPs] and insertion deletion polymorphisms [indels], explaining what these differences are likely to mean [annotation], and explaining the technical stuff. We especially want to work with families to use genome information to understand better the basis of health, attributes and disease. For more information about these options, contact us.