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Medicago Hapmap

Medicago truncatula forms symbiotic interactions with nitrogen fixing bacteria and mycorrhizal fungi. In order to better understand the genes driving symbiosis as well as other important traits, we resequenced ~285 and identified variants in inbred lines spanning the range of Medicago diversity. In addition, we sequenced and de novo assembled 26 Medicago accessions as well as a mycorrhizal symbiont (Glomus versiforme) and 60 nitrogen-fixing rhizobial symbionts. The resulting sequences and variants allow from population genomic studies and connection of genotype to phenotype through genome-wide association studies (GWAS).


  • G. Bauchet, K. Bett, C. Cameron, J. Campbell, E. Cannon, S. Cannon, J. Carlson, A. Chan, A. Cleary, T. Close, D. Cook, A. Cooksey, C. Coyne, S. Dash, R. Dickstein, A. Farmer, D. Fernández-Baca, S. Hokin, E. Jones, Y. Kang, M. Monteros, M. Muñoz-Amatriaín, K. Mysore, C. Pislariu, C. Richards, A. Shi, C. Town, M. Udvardi, E. Wettberg, N. Young and P. Zhao.
    The future of legume genetic data resources: Challenges, opportunities, and priorities
    Legume Science, n/a(n/a), e16, 2019, DOI 10.1002/leg3.16
    Legume Information System  Legume Federation  PeanutBase  Medicago HapMap Project 
  • X. Sun, W. Chen, S. Ivanov, A. MacLean, H. Wight, T. Ramaraj, J. Mudge, M. Harrison and Z. Fei.
    Genome and evolution of the arbuscular mycorrhizal fungus Diversispora epigaea (formerly Glomus versiforme) and its bacterial endosymbionts
    New Phytologist, 221(3), 1556--1573, 2019, DOI 10.1111/nph.15472
    Medicago HapMap Project 
  • K. Moll, P. Zhou, T. Ramaraj, D. Fajardo, N. Devitt, M. Sadowsky, R. Stupar, P. Tiffin, J. Miller, N. Young, K. Silverstein and J. Mudge.
    Strategies for optimizing BioNano and Dovetail explored through a second reference quality assembly for the legume model, Medicago truncatula
    BMC Genomics, 18(1), 2017, DOI 10.1186/s12864-017-3971-4
    Medicago HapMap Project 
  • J. Miller, P. Zhou, J. Mudge, J. Gurtowski, H. Lee, T. Ramaraj, B. Walenz, J. Liu, R. Stupar, R. Denny, L. Song, N. Singh, L. Maron, S. McCouch, W. McCombie, M. Schatz, P. Tiffin, N. Young and K. Silverstein.
    Hybrid assembly with long and short reads improves discovery of gene family expansions
    BMC Genomics, 18(1), 2017, DOI 10.1186/s12864-017-3927-8
    Medicago HapMap Project 
  • P. Zhou, K. Silverstein, T. Ramaraj, J. Guhlin, R. Denny, J. Liu, A. Farmer, K. Steele, R. Stupar, J. Miller, P. Tiffin, J. Mudge and N. Young.
    Exploring structural variation and gene family architecture with De Novo assemblies of 15 Medicago genomes
    BMC Genomics, 18(1), 2017, DOI 10.1186/s12864-017-3654-1
    Legume Federation  Medicago HapMap Project 
  • J. Yoder, R. Briskine, J. Mudge, A. Farmer, T. Paape, K. Steele, G. Weiblen, A. Bharti, P. Zhou, G. May, N. Young and P. Tiffin.
    Phylogenetic Signal Variation in the Genomes of Medicago (Fabaceae)
    Systematic Biology, 62(3), 424--438, 2013, DOI 10.1093/sysbio/syt009
    Medicago HapMap Project 

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